Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Infectious Disease EBV » Anti -Epstein Barr Virus (EBV), Latent Membrane Protein (Mixed clones) (LMP)

Anti -Epstein Barr Virus (EBV), Latent Membrane Protein (Mixed clones) (LMP)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Monoclonal Mouse Supernatant IH
EBV is a human Herpes virus that establishes a life-long persistence in the host. The virus infects the vast majority of the world's adult population and is well known for its association with a broad spectrum of benign and malignant diseases, including infectious mononucleosis, Burkitt's lymphoma, nasopharyngeal carcinoma, and is causally associated with lymphoid and epithelial malignancies, including post-transplant lymphoproliferative disorders, Hodgkin's disease, anaplastic nasopharyngeal carcinoma and gastric carcinomas. Latent membrane protein 1 (LMP1) of Epstein-Barr virus (EBV) is a transforming protein that affects multiple cell signalling pathways and contributes to EBV-associated oncogenesis. LMP1 can be expressed in some states of EBV latency, and significant induction of full-length LMP1 is also observed frequently during virus reactivation into the lytic cycle. LMP1 is critical for EBV-infected cell activation, adhesion and survival, and is usually expressed in the malignant cells.
Catalog #E3440-32D1
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (frozen and paraffin): 1:100-1:200.
Requires protein digestion pre-treatment of paraffin sections (e.g. trypsin). Optimal dilutions to be determined by the researcher.
Hybridoma3X63-Ag8.653 myeloma cells with spleen cells from Balb/c mice.
Storage and StabilityLyophilized powder may be stored at -20°C. Reconstitute with sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone NoMixed clones
HostMouse
ConcentrationNot determined
FormSupplied as a lyophilized powder, 15mM Sodium Azide. Reconstitute with 1ml ddH2O.
PuritySupernatant
ImmunogenRecombinant fusion protein of bacterial beta-galactosidase and EBV LMP-1
SpecificityA cocktail of 4 antibodies recognizing different epitopes of Epstein Barr Virus LMP. This product stains EBV positive lymphoblastoid cell lines and EBV infected B cells in infectious mononucleosis.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links