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You are here:Home » Antibodies » Abs to Infectious Disease EBV » Anti -EBV-Induced Gene 3 (EBI3, Interleukin-27 subunit beta, IL-27 subunit beta, IL-27B, Epstein-Barr virus-induced gene 3 protein)

Anti -EBV-Induced Gene 3 (EBI3, Interleukin-27 subunit beta, IL-27 subunit beta, IL-27B,
Epstein-Barr virus-induced gene 3 protein)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E
Epstein-Barr virus-induced gene protein 3 (EBI3), also known as Interleukin-27 beta chain (IL27B) is a widely expressed homolog to the interleukin IL-12p40 subunit protein. It forms a heterodimer with either IL-12p35 or an IL-12p35 homologue, IL27-p28 (also called IL-28), to create a new cytokine (IL-27). IL-27 plays an important function in regulating the activity of B and T lymphocytes. It drives rapid clonal expansion of naive CD4(+) T-cells and strongly synergizes with IL-12 to trigger IFN-gamma production of naive CD4(+) T-cells. The human Ebi3 encodes a secreted glycoprotein that is expressed in the spleen and tonsils, and at high levels in full-term placenta.
Catalog #E3440-50A
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:32000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris, pH 7.2, 0.5% BSA, 0.02% sodium azide.
PurityPurified by affinity chromatography.
ImmunogenSynthetic peptide with sequence C-IRYKRQGAARFHR, from the internal region of human EBI3 (NP_005746.2).
SpecificityRecognizes human EBI3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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