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Abs to Infectious Disease EBV
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Anti -EBV-Induced Gene 3 (EBI3, Interleukin-27 subunit beta, IL-27 subunit beta, IL-27B, Epstein-Barr virus-induced gene 3 protein)
Anti -EBV-Induced Gene 3 (EBI3, Interleukin-27 subunit beta, IL-27 subunit beta, IL-27B,
Epstein-Barr virus-induced gene 3 protein)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E |
|
| Epstein-Barr virus-induced gene protein 3 (EBI3), also known as Interleukin-27 beta chain (IL27B) is a widely expressed homolog to the interleukin IL-12p40 subunit protein. It forms a heterodimer with either IL-12p35 or an IL-12p35 homologue, IL27-p28 (also called IL-28), to create a new cytokine (IL-27). IL-27 plays an important function in regulating the activity of B and T lymphocytes. It drives rapid clonal expansion of naive CD4(+) T-cells and strongly synergizes with IL-12 to trigger IFN-gamma production of naive CD4(+) T-cells. The human Ebi3 encodes a secreted glycoprotein that is expressed in the spleen and tonsils, and at high levels in full-term placenta. | | | Catalog # | E3440-50A | | Applications | Suitable for use in ELISA. Other applications not tested. | | Recommended Dilution | ELISA: 1:32000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris, pH 7.2, 0.5% BSA, 0.02% sodium azide. | | Purity | Purified by affinity chromatography. | | Immunogen | Synthetic peptide with sequence C-IRYKRQGAARFHR, from the internal region of human EBI3 (NP_005746.2). | | Specificity | Recognizes human EBI3. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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