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You are here:Home » Antibodies » Abs to Oncoproteins » Anti -ErbB2 (Tyr1248) (Receptor Tyrosine-protein Kinase erbB-2, p185erbB2, Proto-oncogene C-erbB-2, Proto-oncogene NEU, Tyrosine Kinase-type Cell Surface Receptor HER2, Metastatic Lymph Node Gene 19 Protein MLN 19, HER2, NEU, NGL)

Anti -ErbB2 (Tyr1248) (Receptor Tyrosine-protein Kinase erbB-2, p185erbB2, Proto-oncogene
C-erbB-2, Proto-oncogene NEU, Tyrosine Kinase-type Cell Surface Receptor HER2, Metastatic
Lymph Node Gene 19 Protein MLN 19, HER2, NEU, NGL)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
ErbB2, a member of the EGF receptor family, is an essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. This protein is not activated by EGF, TGF-alpha and amphiregulin. ErbB2 potentially forms a heterodimer with each of the other ERBB receptors. An interaction with PRKCABP has been suggested. Ligand-binding to this Type I membrane protein may increase phosphorylation on tyrosine residues.
Catalog #E3451-26G
ApplicationsSuitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:1,000
Western Blot: 1:50-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic non-phosphopeptide corresponding to amino acid residues surrounding Tyr1248 of human ERBB2 (KLH).
SpecificityRecognizes human ERBB2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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