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Anti -ErbB3 (Receptor Tyrosine-protein Kinase erbB-3, Proto-oncogene-like Protein C-ErbB-3, Tyrosine Kinase-type Cell Surface Receptor HER3, HER3)
Anti -ErbB3 (Receptor Tyrosine-protein Kinase erbB-3, Proto-oncogene-like Protein
C-ErbB-3, Tyrosine Kinase-type Cell Surface Receptor HER3, HER3)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
IF |
|
| c-erbB-3/HER-3 is the third member of the type I family of growth factor receptors. It binds to ligands in the heregulin family. c-erbB-3 is over-expressed in a variety of tumors including breast, stomach, pancreas and colon. Heregulin & EGF stimulate tyrosine phosphorylation of c-erbB-3 to different extents. | | | Catalog # | E3451-35A | | Applications | Suitable for use in Immunofluorescence. Other applications not tested. | | Recommended Dilution | Immunofluorescence: 1:100-1:200 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic non-phosphopeptide corresponding to human Her3/ErbB3 around the phosphorylation site of Tyr1289 (Q-G-YP-E-E). | | Specificity | Recognizes human ErbB3. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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