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You are here:Home » Antibodies » Abs to Oncoproteins » Anti -ErbB3 (Receptor Tyrosine-protein Kinase erbB-3, Proto-oncogene-like Protein C-ErbB-3, Tyrosine Kinase-type Cell Surface Receptor HER3, HER3)

Anti -ErbB3 (Receptor Tyrosine-protein Kinase erbB-3, Proto-oncogene-like Protein
C-ErbB-3, Tyrosine Kinase-type Cell Surface Receptor HER3, HER3)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IF
c-erbB-3/HER-3 is the third member of the type I family of growth factor receptors. It binds to ligands in the heregulin family. c-erbB-3 is over-expressed in a variety of tumors including breast, stomach, pancreas and colon. Heregulin & EGF stimulate tyrosine phosphorylation of c-erbB-3 to different extents.
Catalog #E3451-35A
ApplicationsSuitable for use in Immunofluorescence. Other applications not tested.
Recommended DilutionImmunofluorescence: 1:100-1:200
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic non-phosphopeptide corresponding to human Her3/ErbB3 around the phosphorylation site of Tyr1289 (Q-G-YP-E-E).
SpecificityRecognizes human ErbB3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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