Anti -ErbB3 (ERBB3, v-erb-b2 Erythroblastic Leukemia Viral Oncogene Homolog 3 avian,
HGNC:3431, ErbB-3, HER3, MDA-BF-1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3)
(BSA & Azide Free)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
B IP |
|
| c-erbB-3/HER-3 is the third member of the type I family of growth factor receptors. It binds to ligands in the heregulin family. c-erbB-3 is over-expressed in a variety of tumors including breast, stomach, pancreas, and colon. Heregulin & EGF stimulate tyrosine phosphorylation of c-erbB-3 to different extents. | | | Catalog # | E3451-35EX | | MW of Antigen | 185kD | | Epitope | aa1234-1259 | | Applications and Working Dilutions | Immunoprecipitation (Denatured verified) (Use Protein G) (Ab 2ug/mg protein lysate) | | Western Blotting (Ab 1-2ug/ml for 2hrs at RT) The optimal dilution for a specific application under a given set of experimental conditions should be determined by the investigator. | | Positive Control | T47D, SKBR3 or MAD109 cells. | | Cellular Localization | Cytoplasmic and cell membrane | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at-20°C or colder. Aliquots are stable for at least 12 months at-20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 3F165 | | Host | Mouse | | Source | Rat | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in 10mM PBS, pH 7.4. Also available with BSA and azide. See E3451-35E | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Recombinant rat c-erbB-3/HER-3 oncoprotein | | Specificity | For optimum results, immunoprecipitate with erbB-3 and Western blot Species Crossreactivity: human, rat, mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -ErbB3 (ERBB3, v-erb-b2 Erythroblastic Leukemia Viral Oncogene Homolog 3 avian, HGNC:3431, ErbB-3, HER3, MDA-BF-1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3) (BSA & Azide Free) |
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