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You are here:Home » Antibodies » Abs to Oncoproteins » Anti -ErbB3, CT (Receptor Tyrosine-protein Kinase erbB-3, Proto-oncogene-like Protein c-ErbB-3, Tyrosine Kinase-type Cell Surface Receptor HER3, HER3)

Anti -ErbB3, CT (Receptor Tyrosine-protein Kinase erbB-3, Proto-oncogene-like Protein
c-ErbB-3, Tyrosine Kinase-type Cell Surface Receptor HER3, HER3)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B IH
c-erbB-3/HER-3 is the third member of the type I family of growth factor receptors. It binds to ligands in the heregulin family. c-erbB-3 is over-expressed in a variety of tumors including breast, stomach, pancreas and colon. Heregulin & EGF stimulate tyrosine phosphorylation of c-erbB-3 to different extents.
Catalog #E3451-35G1
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:32,000
Western Blot: 0.1-0.3ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in TBS, 0.5% BSA, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to HSRLFPKANAQRT of ERBB3 at C-terminal (KLH).
SpecificityRecognizes human ERBB3. Species sequence homology: Canine, mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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