Anti -ErbB3, phosphorylated (Tyr1289) (ERBB3, v-erb-b2 Erythroblastic Leukemia Viral
Oncogene Homolog 3 avian, HGNC:3431, ErbB-3, HER3, MDA-BF-1, c-erbB-3, c-erbB3, erbB3-S,
p180-ErbB3, p45-sErbB3)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rabbit |
Supernatant |
B IC |
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| HER3/ErbB3 is a member of the ErbB/EGF receptor protein tyrosine kinase family (1,2). Tyrosine phosphorylation of HER3/ErbB3 depends on its association with other ErbB tyrosine kinases (3). Phosphorylation sites in the carboxy-terminal tail mediate downstream signaling | | | pathways. HER3/ErbB3 is highly expressed in many cancer cells (4), and it may work together with other Erb members in tumorogenesis and proliferation (5). HER/ErbB3 is phosphorylated by EGFR or ErbB2 through dimeric interactions with HER/ErbB3, on Tyrosine 1289, a docking | | | site for phosphatidylinositol 3-kinase (6). | | | Catalog # | E3451-36E | | Applications | Suitable for use in Immunocytochemistry and Western Blot. Other applications not tested. | | Recommended Dilution | Immunocytochemistry: 1:100 | | Western Blot: 1:2500-1:5000 | | Optimal dilution determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG | | Clone No | 9H345 | | Host | Rabbit | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid in 50mM Tris-glycine, pH 7.4, 0.15M sodium chloride, 40% glycerol, 0.01% sodium azide, 0.05% BSA. | | Purity | Supernatant. | | Immunogen | A phospho-specific peptide corresponding to residues surrounding Tyrosine 1289 of human HER3/ErbB3. | | Specificity | Recognizes human HER3/ErbB3 phosphorylated on Tyrosine 1289. | | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | v-erb-b2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (avian), HGNC:3431, ErbB-3, MDA-BF-1, c-erbB-3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3 |
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Download Specifications for Anti -ErbB3, phosphorylated (Tyr1289) (ERBB3, v-erb-b2 Erythroblastic Leukemia Viral Oncogene Homolog 3 avian, HGNC:3431, ErbB-3, HER3, MDA-BF-1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3) |
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