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You are here:Home » Antibodies » Abs to Oncoproteins » Anti -ErbB3, phosphorylated (Tyr1289) (ERBB3, v-erb-b2 Erythroblastic Leukemia Viral Oncogene Homolog 3 avian, HGNC:3431, ErbB-3, HER3, MDA-BF-1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3)

Anti -ErbB3, phosphorylated (Tyr1289) (ERBB3, v-erb-b2 Erythroblastic Leukemia Viral
Oncogene Homolog 3 avian, HGNC:3431, ErbB-3, HER3, MDA-BF-1, c-erbB-3, c-erbB3, erbB3-S,
p180-ErbB3, p45-sErbB3)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IC
HER3/ErbB3 is a member of the ErbB/EGF receptor protein tyrosine kinase family (1,2). Tyrosine phosphorylation of HER3/ErbB3 depends on its association with other ErbB tyrosine kinases (3). Phosphorylation sites in the carboxy-terminal tail mediate downstream signaling
pathways. HER3/ErbB3 is highly expressed in many cancer cells (4), and it may work together with other Erb members in tumorogenesis and proliferation (5). HER/ErbB3 is phosphorylated by EGFR or ErbB2 through dimeric interactions with HER/ErbB3, on Tyrosine 1289, a docking
site for phosphatidylinositol 3-kinase (6).
Catalog #E3451-36E
ApplicationsSuitable for use in Immunocytochemistry and Western Blot. Other applications not tested.
Recommended DilutionImmunocytochemistry: 1:100
Western Blot: 1:2500-1:5000
Optimal dilution determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
IsotypeIgG
Clone No9H345
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in 50mM Tris-glycine, pH 7.4, 0.15M sodium chloride, 40% glycerol, 0.01% sodium azide, 0.05% BSA.
PuritySupernatant.
ImmunogenA phospho-specific peptide corresponding to residues surrounding Tyrosine 1289 of human HER3/ErbB3.
SpecificityRecognizes human HER3/ErbB3 phosphorylated on Tyrosine 1289.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesv-erb-b2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (avian), HGNC:3431, ErbB-3, MDA-BF-1, c-erbB-3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3


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