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Anti -ErbB4 (c-erbB4, HER4) (BSA & Azide Free)
Anti -ErbB4 (c-erbB4, HER4) (BSA & Azide Free)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
IP FC |
|
| c-erbB-4 is the fourth member of class I receptor kinase family (ErbB). Down regulation of ErbB-4 in estrogen receptor-positive cancer cells inhibits proliferation. | | | Catalog # | E3451-40AX | | Applications | Suitable for use in Flow Cytometry, Immunoprecipitation, accelerartes Internalization of c-erbB-4 and stimulation of tyrosine kinase activity. Not suitable for use in Western Blot. Other applications have not been tested. | | Recommended Dilution | Immunoprecipitation: 2ug/mg protein lysate (Use Protein G). (Unoccupied as well as the occupied c-erbB-4 receptor). | | Optimal dilutions to be determined by the researcher. | | Positive Control | T47D or MDA-MB-453 cells | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 3F166 | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4. Also available with BSA and azide. See E3451-40A | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Extracellular fragment of recombinant human c-erbB-4/HER-4 oncoprotein. | | Cellular Localization | Cell membrane and cytoplasmic MW of Antigen: 185kD | | | Specificity | Recognizes human c-erbB-4/HER-4 oncoprotein. Species Crossreactivity: mouse and rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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