Anti -ERC1, NT (ELKS/Rab6-interacting/CAST Family Member 1, ERC-1, Cast2, ELKS, FLJ31750,
KIAA1081, MGC12974, Rab6-interacting Protein 2, RAB6IP2)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E B |
|
| ERC1 (ELKS/Rab6interacting/CAST family member 1), otherwise known as ELKS, is a widely expressed member of the RIMbinding protein family, which can be recruited on Golgi membranes by RAB6A, and may be involved in Rab6 regulated endosomes to Golgi transport. | | | ERC1 is as an essential regulatory subunit of the IkappaB kinase (IKK) complex, a key enzyme in activation of nuclear factor kappaB (NFkappaB). ERC1 is highly expressed in the brain, testis and thyroid, and is implicated in the formation of the cytomatrix at the active zone (CAZ), believed to define the site of calciumdependent exocytosis of neurotransmitters. | | | Catalog # | E3451-49 | | Applications | Suitable for use in ELISA and Western Blot. Other applications have not been tested. | | Recommended Dilutions | | | ELISA: 1:128,000 | | Western Blot: 0.1-0.3ug/ml detects a band of ~90kD in human pancreas cell lysates. | | Optimal dilutions to be determined by the researcher. | | | | Storage and Stability: | | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris, pH 7.3, 0.5% BSA, 0.02% sodium azide. | | Purity | Purified by affinity chromatography. | | Immunogen | Synthetic peptide corresponding to YGSARSVGKVEPSC from the NTerminal region of ERC1 (NP_829883.1; NP_829884.1). | | Specificity | Recognises an epitope within the Nterminal (NT) region of human ERC1. Species sequence homology: canine, bovine, mouse, rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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