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You are here:Home » Molecular Biology » MB-Protein Kinase Inhibitors » Erlotinib Hydrochloride

Erlotinib Hydrochloride

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Specifications

Inhibitor of the epidermal growth factor receptor tyrosine kinase, which is highly expressed and occasionally mutated in various forms of cancer. Erlotinib binds reversibly to the ATP binding site of the receptor.
Catalog #E3452-75
SolubilitySoluble in DMSO at 18mg/ml with warming; very poorly soluble in ethanol; very poorly soluble in water; maximum solubility in plain water is estimated to be about 5-20uM; buffers, serum, or other additives may increase or decrease the aqueous solubility.
Elemental Analysis (Calculated)C: 61.46%
H: 5.63%
Cl: 8.25%
N: 9.77%
Storage and StabilityMay be stored at RT for short-term only. Long-term storage is recommended at -20°C. Stable for 6 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
CAS Number183319-69-9
Molecular FormulaC22H23N3O4•HCl
Molecular Weight429.90
PurityHPLC, TLC: ~99%
FormSupplied as a white to off-white powder
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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