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Erythropoietin, alpha, Recombinant, Human (Liquid) (EPO, EPO-a, EPO-alpha, Epoetin, EP, MGC138142)
Erythropoietin, alpha, Recombinant, Human (Liquid) (EPO, EPO-a, EPO-alpha, Epoetin, EP,
MGC138142)
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| Erythropoietin, ~34-36kD, normally produced in the kidney and liver, is the principle hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Indicated for treatment of neutropenia or anemia secondary to ZDV- or Ganciclovir-induced bone marrow suppression (most effective in patients with endogenous EPO levels < 500 IU/ml). | | | Catalog # | E3455-07A1 | | Dimers and Aggregates | 1% as determined by silver stained SDS-PAGE gel analysis. | | Biological Activity | Fully biologically active when compared to standard. | | Specific Activity (Normocythaemic mice) | ~120,000 IU/mg. | | Storage and Stability | Aliquot to avoid repeated freezing and thawing and freeze at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 12 months. | | Molecular Weight | 34-36kD | | Source | Recombinant Human in Chinese hamster ovary (CHO) cells | | Purity | Chromatographically purified. 98% by RP-HPLC, Anion-exchange FPLC. Analyzed by reducing and non-reducing SDS-PAGE, Silver Stained. Endotoxin: 0.1ng/ug (IEU/ug) | | Concentration | ~0.1mg/ml | | Form | Supplied as a liquid in sodium citrate, sodium chloride, citric acid buffer. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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