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You are here:Home » Antibodies » Antibodies-Biochemicals » Anti -Ethenoadenosine

Anti -Ethenoadenosine


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Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IP IH FC
The reaction of chloroacetaldehyde (CAA) with DNA results in the formation of ethenoadenosine also known as 1,N6-ethenodeoxy-adenosine or etheno-A. CAA is formed through metabolization of for example vinyl chloride, a well established carcinogen. In RNA, after in vitro activation, etheno-A and etheno-C are the principle products of RNA damage. Etheno derivate formation may be highest in single-stranded DNA-regions.
Catalog #E8490
ApplicationsCan be used for Immunoprecipitation, Western Blot and Flow Cytometry. Useful for Immunohistology on frozen sections and immunoassays.
Recommended DilutionImmunohistology: 1:10
Flow Cytometry: 1:10
Western Blot: 1:10
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20°C or colder. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
Clone No6A544
FormSupplied as a liquid in PBS, containing 0.02% sodium azide and 0.1% BSA.
PurityPurified IgG
SpecificityReacts with both the ribose and deoxyribose form of the adduct. Not crossreactive with non-modified DNA or the normal nucleotides.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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