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You are here:Home » Antibodies » Abs to Translation Initiation Factors » Anti -Eukaryotic Translation Initiation Factor 3, Subunit 4 (eIF3S4, eIF-3 delta, eIF-3 RNA Binding Subunit, eIF3 p42, eIF3 p44, eIF3g)

Anti -Eukaryotic Translation Initiation Factor 3, Subunit 4 (eIF3S4, eIF-3 delta, eIF-3
RNA Binding Subunit, eIF3 p42, eIF3 p44, eIF3g)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP
Eukaryotic initiation factor 3 subunit G (eIF3G) is one of at least 13 non-identical protein subunits of eukaryotic initiation factor 3 (eIF3). eIF3 is the largest eIF (~650 kDa) and functions to facilitate binding of the 40S ribosomal subunit to the 5-end of cellular mRNAs near the cap structure (m7GpppN). eIF3G has been shown to directly interact with AIF (apoptosis inducing factor), a protein that plays a role in caspase-independent apoptosis. AIF is able to inhibit protein synthesis via its interaction with eIF3g.
Applications:
Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested.
Catalog #E8949-36A
Recommended DilutionWestern Blot: 1:2000-1:10000
Immunoprecipitation: 2-5ug/mg lysate
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.2mg/ml
FormSupplied as a liquid in tris-buffered saline, 0.1% BSA, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to a region between residue 1-50 of human eukaryotic translation initiation factor 3, subunit G (eukaryotic translation initiation factor 3, subunit 4 (eukaryotic translation initiation factor 3, subunit G) (NP_003746.2).
SpecificityRecognizes human EIF3S4.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesEukaryotic Translation Initiation Factor 3 Subunit G, Eukaryotic Translation Initiation Factor 3 Subunit p42 (delta 44kD)


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