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Anti -Exosome Component 2 (EXOSC2, Exosome Complex Exonuclease RRP4, p7, Ribosomal RNA-processing Protein 4, RRP4, hRrp4p, Rrp4p)
Anti -Exosome Component 2 (EXOSC2, Exosome Complex Exonuclease RRP4, p7, Ribosomal
RNA-processing Protein 4, RRP4, hRrp4p, Rrp4p)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E |
|
| The exosome, present in both the nucleus and cytoplasm of all eukaryotic cells, is a complex of 3'-5' exoribonucleases containing at least nine core components. Recently, it has been demonstrated, mainly by analyses in yeast, that the nuclear exosome is essential for rRNA processing and sn(o)RNA biogenesis. Furthermore, it is involved in the degradation of improperly processed mRNAs. The cytoplasmic exosome participates in normal mRNA turnover and in the degradation of inherently instable mRNAs that contain AU-rich elements. Therefore, the exosome plays a key role in RNA metabolism. | | | Catalog # | E9008-50A | | Applications | Suitable for use in ELISA. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with ddH2O to 0.1-1ml. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 15B3 | | Host | Mouse | | Source | Human | | Concentration | Not determined. | | Form | Supplied as a lyophilized powder in 10mM ammonium bicarbonate buffer. Reconstitute with ddH2O to 0.1-1ml. | | Purity | Purified by Protein A affinity chromatography. | | Immunogen | Human Rrp4. | | Specificity | Recognizes human Rrp4. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | EC=3.1.13.- |
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