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You are here:Home » Antibodies » Abs to Ribosomal Proteins » Anti -Exosome Component 2 (EXOSC2, Exosome Complex Exonuclease RRP4, p7, Ribosomal RNA-processing Protein 4, RRP4, hRrp4p, Rrp4p)

Anti -Exosome Component 2 (EXOSC2, Exosome Complex Exonuclease RRP4, p7, Ribosomal
RNA-processing Protein 4, RRP4, hRrp4p, Rrp4p)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E
The exosome, present in both the nucleus and cytoplasm of all eukaryotic cells, is a complex of 3'-5' exoribonucleases containing at least nine core components. Recently, it has been demonstrated, mainly by analyses in yeast, that the nuclear exosome is essential for rRNA processing and sn(o)RNA biogenesis. Furthermore, it is involved in the degradation of improperly processed mRNAs. The cytoplasmic exosome participates in normal mRNA turnover and in the degradation of inherently instable mRNAs that contain AU-rich elements. Therefore, the exosome plays a key role in RNA metabolism.
Catalog #E9008-50A
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with ddH2O to 0.1-1ml. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No15B3
HostMouse
SourceHuman
ConcentrationNot determined.
FormSupplied as a lyophilized powder in 10mM ammonium bicarbonate buffer. Reconstitute with ddH2O to 0.1-1ml.
PurityPurified by Protein A affinity chromatography.
ImmunogenHuman Rrp4.
SpecificityRecognizes human Rrp4.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesEC=3.1.13.-


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