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Anti -Ezrin, phosphorylated (Thr353) (Radixin, Moesin, Cytovillin, p81, Membrane-organizing extension spike protein)
Anti -Ezrin, phosphorylated (Thr353) (Radixin, Moesin, Cytovillin, p81,
Membrane-organizing extension spike protein)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IH |
|
| ERM (Ezrin-Radixin-Moesin) proteins function as plasma membrane-actin cytoskeleton linkers and participate in the formation of specialized domains of the plasma membrane. One function of ezrin is in determining survival of epithelia cells by activating the P1-3-kinase/Akt pathway. | | | Catalog # | E9100-02A | | Applications | Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 1:500-1:1000 | | Immunohistochemistry: 1:50-1:100 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4, 150mM sodium chloride, 0.02% sodium azide and 50% glycerol. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthesized phosphopeptide derived from human Ezrin around the phosphorylation site of tyrosine 353 (Q-D-YP-E-E) | | Specificity | Detects endogenous levels of Ezrin only when phosphorylated at tyrosine 353. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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