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You are here:Home » Antibodies » Abs to Actin Related Proteins » Anti -Ezrin, Radixin, Moesin, (p81, Membrane-organizing extension spike protein, NHERF, Na+/H+ exchanger regulatory factor, ERM, ezrin/radixin/moesin)

Anti -Ezrin, Radixin, Moesin, (p81, Membrane-organizing extension spike protein, NHERF,
Na+/H+ exchanger regulatory factor, ERM, ezrin/radixin/moesin)

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IP IH IC
Erzin, a member of the Ezrin, Radixin, Moesin (ERM) family, is a linker protein located between cell surface receptors, adhesion molecules, and actin cytoskeleton (1-2). Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. Recent cloning of the murine and porcine radixin cDNAs revealed a protein highly homologous to ezrin and moesin (3). oesin (membrane-organizing extension spike protein) has previously been characterized as a possible receptor protein for heparan sulfate and also as a cytoskeletal linker protein that stabilizes cell surface microvilli, filopodia and lamellipodia. Data indicate that moesin is identical to the 77-kD band that copurifies with ezrin in its isolation from human placenta (4).
Applications:
Suitable for use in Western Blot, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry. Other applications not tested.
Catalog #E9100-03D
Recommended DilutionsWestern Blot: 1:1000
Immunohistochemistry: 1:100-250
Immunocytochemistry: 1:250-500
Immunoprecipitation: 1:40
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
IsotypeIgG
Clone No9E298
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in 50mM Tris-glycine, pH 7.4, 0.15M sodium chloride, 40% glycerol, 0.01% sodium azide, 0.05% BSA.
PuritySupernatant
ImmunogenA synthetic peptide corresponding to residues surrounding Thr566 (Ezrin 81 kD) Thr564 (Radixin 81 kD) and Thr558 (Moesin 75 kD) of human Ezrin, Radixin and Moesin.
SpecificityRecognizes all 3 proteins.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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