You are here:Home
»
Antibodies
»
Abs to Coagulation Factors
»
Anti -Factor VII (F.VII, Stable Factor, Proconvertin)
Anti -Factor VII (F.VII, Stable Factor, Proconvertin)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rat |
Highly Purified |
E B |
|
| Coagulation factor VII is synthesized in the liver and circulates in the plasma where it binds to tissue factor (TF) and is rapidly converted into VIIa. The resulting 1:1 complex of VIIa and TF initiates the coagulation pathway and also has important coagulation-independent functions such as angiogenesis. The predominant splicing variant of Factor VII in normal liver corresponds to the 444 amino acid precursor. After cleavage of a signal peptide (residues 1 to 38), the mature chain can be further processed into the light chain (residues 39 to 190) and the heavy chain (residues 191 to 444). | | | Catalog # | F0015-01 | | Applications | Suitable for ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | ELISA: Recombinant | | Western Blot: Recombinant Factor VII or Factor VIIa and native Factor VII (Non-reduced) | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 7H80 | | Host | Rat | | Source | Mouse | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in 50% glycerol, H2O. | | Purity | Purified by gel filtration and ion exchange chromatography. | | Immunogen | Purified Factor VII. | | Specificity | Recognizes mouse Factor VII. Also recognizes VIIa (non-reduced Western Blot only). Species crossreactivity: Does not crossreact with human Factor VII or Factor VIIa. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
