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Anti -Factor VII (Coagulation Factor VII, F7, Eptacog alfa, Proconvertin, Serum Prothrombin Conversion Accelerator, SPCA)
Anti -Factor VII (Coagulation Factor VII, F7, Eptacog alfa, Proconvertin, Serum
Prothrombin Conversion Accelerator, SPCA)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Serum |
E |
|
| Coagulation factor VII is synthesized in the liver and circulates in the plasma where it binds to tissue factor (TF) and is rapidly converted into VIIa. The resulting 1:1 complex of VIIa and TF initiates the coagulation pathway and also has important coagulation-independent functions such as angiogenesis. The predominant splicing variant of Factor VII in normal liver corresponds to the 444aa precursor. After cleavage of a signal peptide (residues 1-38), the mature chain can be further processed into the light chain (residues 39-190) and the heavy chain (residues 191-444). | | | Catalog # | F0015-01C | | Applications | Suitable for use in ELISA, Immunoelectrophoresis and single and double radial immunodiffusion. Other applications not tested. | | Recommended Dilution | Immunoelectrophoresis: 2ml plasma or equivalent against 120ml antiserum | | Double Radial Immunodiffusion: Use a rosette arrangement with 10ml antiserum in 3mm | | diameter center well and 2ml plasma samples (neat and serially diluted) in 2mm diameter | | peripheral wells. | | Single Radial Immunodiffusion: 1% in the gel. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | Not determined | | Form | Supplied as a lyophilized powder in PBS, pH 7.2. Preservative free. Reconstitute with 1ml sterile dH2O. | | Purity | Serum | | Immunogen | Purified from plasma. | | Specificity | Recognizes human Coagulation Factor VII. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Coagulation Factor VII (Serum Prothrombin Conversion Accelerator), EC=3.4.21.21 |
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