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Anti -Factor VII (F.VII, Stable Factor, Proconvertin)
Anti -Factor VII (F.VII, Stable Factor, Proconvertin)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Sheep |
Highly Purified |
E B |
|
| Coagulation factor VII is synthesized in the liver and circulates in the plasma where it binds to tissue factor (TF) and is rapidly converted into VIIa. The resulting 1:1 complex of VIIa and TF initiates the coagulation pathway and also has important coagulation-independent functions such as angiogenesis. The predominant splicing variant of Factor VII in normal liver corresponds to the 444 amino acid precursor. After cleavage of a signal peptide (residues 1 to 38), the mature chain can be further processed into the light chain (residues 39 to 190) and the heavy chain (residues 191 to 444). | | | Catalog # | F0015-10 | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Sheep | | Source | Human | | Concentration | ~10mg/ml | | Form | Supplied as a liquid in 20mM HEPES, 0.15M sodium chloride, pH 7.4, 50% glycerol. | | Purity | 98% No contaminants detected. Single band by SDS-PAGE, IEP, and/or RID. Purified by solid phase chromatography. | | Immunogen | Human Factor VII | | Specificity | Recognizes human Factor VII and VIIa. Will react in Western Blot to both reduced and oxidized forms of the protein. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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