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You are here:Home » Antibodies » Abs to Coagulation Factors » Anti -Factor VII (F.VII, Stable Factor, Proconvertin)

Anti -Factor VII (F.VII, Stable Factor, Proconvertin)

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Specifications

Clone Host Grade Applications
Polyclonal Sheep Highly Purified E B
Coagulation factor VII is synthesized in the liver and circulates in the plasma where it binds to tissue factor (TF) and is rapidly converted into VIIa. The resulting 1:1 complex of VIIa and TF initiates the coagulation pathway and also has important coagulation-independent functions such as angiogenesis. The predominant splicing variant of Factor VII in normal liver corresponds to the 444 amino acid precursor. After cleavage of a signal peptide (residues 1 to 38), the mature chain can be further processed into the light chain (residues 39 to 190) and the heavy chain (residues 191 to 444).
Catalog #F0015-10
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostSheep
SourceHuman
Concentration~10mg/ml
FormSupplied as a liquid in 20mM HEPES, 0.15M sodium chloride, pH 7.4, 50% glycerol.
Purity98% No contaminants detected. Single band by SDS-PAGE, IEP, and/or RID. Purified by solid phase chromatography.
ImmunogenHuman Factor VII
SpecificityRecognizes human Factor VII and VIIa. Will react in Western Blot to both reduced and oxidized forms of the protein.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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