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You are here:Home » Antibodies » Abs to Coagulation Factors » Anti -Factor VIIIc (Antihaemophilic Factor)

Anti -Factor VIIIc (Antihaemophilic Factor)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E
Factor VIII (FVIII) is an essential blood clotting factor also known as anti-hemophilic factor (AHF). In humans, Factor VIII is encoded by the F8 gene. Defects in this gene results in hemophilia A, a well known recessive X-linked coagulation disorder. Factor VIII participates in blood coagulation; it is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids forms a complex that converts factor X to the activated form Xa.
Catalog #F0016-15
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionsOptimal dilutions to be determined by the researcher.
TiterELISA: 1:16,000
Affinity Constant8.0x10e9 L/mol
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No8.F.110
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4. No preservative added.
PurityPurified by Protein A affinity chromatography.
ImmunogenHighly pure human Factor VIIIc
SpecificityRecognizes an epitope in the N-terminal region of the 83kD light chain of Human Factor Vlllc: 100%. Does not recognize human Factor VIII or Factor related antigens.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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