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You are here:Home » Antibodies » Abs to Coagulation Factors » Anti -Factor X

Anti -Factor X

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified E B
Factor X is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.
Catalog #F0018-01B
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
Clone No9L239
HostRat
SourceMouse
ConcentrationAs reported
FormSupplied as a liquid in 50% glycerol.
PurityPurified by Protein G affinity chromatography.
ImmunogenNative purified mouse Factor X.
SpecificityRecognizes mouse Factor X by ELISA but does not react with mouse Factor Xa. By Western blot, recognizes mouse Factor X heavy chain (reduced-strong; non-reduced-weak). Does not cross react with human Factor X or Xa. Does not inhibit PT assay (mouse plasma).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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