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You are here:Home » Antibodies » Abs to Coagulation Factors » Anti -Factor XI

Anti -Factor XI

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Highly Purified E B RIA
Human Factor XI is a plasma glycoprotein which circulates in a non-covalent complex with high molecular weight kininogen. The mature molecule is synthesized in the liver. It is a two-chain homodimer with a molecular weight of ~160kD. It is estimated that 5% of the total mass is attributable to carbohydrate. The two identical monomers have molecular weights of 80kD. They are joined together by disulfide bonds. By SDS-PAGE analysis, factor XI appears as a single band both non-reduced (Mr 160kD) and reduced (Mr 80kD).
Catalog #F0018-61
ApplicationsSuitable for use as an inhibitor in clotting assays, Western Blot, RIA and ELISA. Useful for purification of Factor XI. Other applications not tested.
Recommended DilutionsWestern Blot: Non-reduced samples only
Optimal dilutions to be determined by the researcher.
SourceAscites
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG
Clone No2B32
HostMouse
SourceHuman
Concentration~7mg/ml
FormSupplied as a liquid, 50% glycerol. No preservative added.
PurityPurified by salt fractionation, gel filtration and ion exchange chromatography.
ImmunogenHuman Factor XI
SpecificityRecognizes human Factor XI.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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