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Specifications

Clone Host Grade Applications Monoclonal Mouse Highly Purified E B RIA

Human Factor XI is a plasma glycoprotein which circulates in a non-covalent complex with high molecular weight kininogen. The mature molecule is synthesized in the liver. It is a two-chain homodimer with a molecular weight of ~160kD. It is estimated that 5% of the total mass is attributable to carbohydrate. The two identical monomers have molecular weights of 80kD. They are joined together by disulfide bonds. By SDS-PAGE analysis, factor XI appears as a single band both non-reduced (Mr 160kD) and reduced (Mr 80kD).
Catalog #	F0018-61
Applications	Suitable for use as an inhibitor in clotting assays, Western Blot, RIA and ELISA. Useful for purification of Factor XI. Other applications not tested.
Recommended Dilutions	Western Blot: Non-reduced samples only
	Optimal dilutions to be determined by the researcher.
Source	Ascites
Storage and Stability	May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone Type	Monoclonal
Isotype	IgG
Clone No	2B32
Host	Mouse
Source	Human
Concentration	~7mg/ml
Form	Supplied as a liquid, 50% glycerol. No preservative added.
Purity	Purified by salt fractionation, gel filtration and ion exchange chromatography.
Immunogen	Human Factor XI
Specificity	Recognizes human Factor XI.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.