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You are here:Home » Antibodies » Abs to Coagulation Factors » Anti -Factor XIIIa (Fibrinoligase, Plasma Transglutaminase, Fibrin Stabilizing Factor) (BSA & Azide Free)

Anti -Factor XIIIa (Fibrinoligase, Plasma Transglutaminase, Fibrin Stabilizing Factor)
(BSA & Azide Free)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IH
Factor XIII is a beta-globulin found in plasma. It is composed of two subunits. Factor XIIIa is the catalytic subunit. It is a dimer of MW 160kD. Factor XIII is present in plasma as an a2b2 heterodimer (MW 320kD). In platelets, only the a2 unit exists. Factor XIIIa is a dermal dendrocyte marker. It shows variable reaction with these types of tumors. It can be used for histiocytic phenotyping and has been reported to mark capillary hemangiomas and tumors of the central nervous system. Factor XIII has also been used with CD34 to differentiate between dermatofibroma and dermatofibrosarcoma protuberans.
Catalog #F0019-50FX
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1-2ug/ml for 2hrs at RT.
Immunohistochemistry (Formalin/paraffin): 1:100 for 20 minutes at RT using the LP system, 30 minutes at RT using UltraVision. No special pretreatment is required for staining of formalin-fixed, paraffin-embedded tissues.
Optimal dilutions to be determined by the researcher.
Positive ControlRecombinant human Factor XIII a-subunit, capillary hemangioma, dermatofibroma and placenta.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No3F177
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4. Also available with BSA and azide. See F0019-50F.
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant protein corresponding to a-subunit of coagulation Factor XIII. Cellular Localization
SpecificityRecognizes human reduced (80kD) and unreduced (160kD) forms of Factor XIII. Does not recognize human Factor XIII B-chain or human Factor XII.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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