You are here:Home
»
Antibodies
»
Abs to Coagulation Factors
»
Anti -Factor XIIIa (Fibrinoligase, Plasma Transglutaminase, Fibrin Stabilizing Factor) (Glycerol Free)
Anti -Factor XIIIa (Fibrinoligase, Plasma Transglutaminase, Fibrin Stabilizing Factor)
(Glycerol Free)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IH |
|
| Factor XIII is a beta-globulin found in plasma and is composed of two subunits. Factor XIIIa is the catalytic subunit and is a dimer of MW 160kD. Factor XIII is present in plasma as an a2b2 heterodimer (M.W. 320kD); whereas in platelets, only the a2 unit exists. Factor XIIIa is a dermal dendrocyte marker and shows variable reaction with these types of tumors. It can be used for histiocytic phenotyping and has been reported to mark capillary hemangiomas and tumors of the central nervous system. Factor XIII has also been used with CD34 to differentiate between dermatofibroma and dermatofibrosarcoma protuberans. | | | Catalog # | F0019-50G | | Applications | Suitable for use in Western Blot and Immunohistochemistry. Other applications have not been tested. | | Recommended Dilution | Western Blot: 5-10ug/ml for 2 hours at RT | | Immunohistochemistry (Formalin/paraffin): 10-20ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes. | | Optimal dilutions to be determined by the researcher. | | Positive Control | Human recombinant Factor XIIIa. Capillary hemangioma, dermatofibroma, and placenta. | | Storage and Stability | For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide. Also available without BSA and azide. See F0019-50GX. | | Purity | Purified by Protein A affinity chromatography. | | Immunogen | Recombinant protein corresponding to A subunit of coagulation Factor XIII. Cellular Localization: Cytoplasmic and nuclear. | | Specificity | Recognizes human Factor XIIIa at ~160kD (non-reduced dimer), ~80kD (reduced monomer). Does not crossreact with human Factor XIII B-chain or human Factor XII. | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
