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You are here:Home » Antibodies » Abs to Tyrosine Kinases » Anti -FAK, phosphorylated (Tyr397, Tyr407, Tyr576, Tyr577, Tyr861) (Focal Adhesion Associated Protein Tyrosine Kinase, BC3)

Anti -FAK, phosphorylated (Tyr397, Tyr407, Tyr576, Tyr577, Tyr861) (Focal Adhesion
Associated Protein Tyrosine Kinase, BC3)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Focal Adhesion Kinase (FAK) is a non-receptor protein tyrosine kinase discovered as a substrate for Src and as a key element of integrin signaling. FAK plays a central role in cell spreading, differentiation, migration, cell death and acceleration of the G1 to S phase transition of the cell cycle.
Catalog #F0019-55J
Phosphorylation site-specific antibodies selective for the phosphorylated forms of focal adhesionkinase (FAK) enzyme containing a phosphate on tyrosine 397, 407, 576, 577 or 861. The antibodies have been shown to recognize FAK (approximately 125kD) in chick embryo fibroblast cells plated on fibronectin.
Kit ComponentsF0019-55J1: FAK (pY397) 1x20ul
F0019-55J2: FAK (pY407) 1x20ul
F0019-55J3: FAK (pY576) 1x20ul
F0019-55J4: FAK (pY577) 1x20ul
F0019-55J5: FAK (pY861) 1x20ul
ApplicationsSuitable for use in Western Blot and Immunostaining. Other applications not tested.
Recommended DilutionsWestern Blot: 1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in Dulbecco’s PBS (without Mg2+ and Ca2+), 1mg/ml BSA (IgG, protease free), pH 7.3, 0.05% sodium azide, 50% glycerol.
PurityPurified by affinity chromatography
ImmunogenChemically synthesized phosphopeptides derived from the regions of FAK containing tyrosine at position 397, 407, 576, 577, or 861.
SpecificityRecognizes phosphorylated forms of focal adhesion kinase (FAK) enzyme containing a phosphate on tyrosine 397, 407, 576, 577, or 861. The antibodies have been shown to recognize FAK (approximately 125kD) in chick embryo fibroblast cells plated on fibronectin. Species Crossreactivity: human, mouse, chicken and frog FAK.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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