Anti -FAK, phosphorylated (Tyr397, Tyr407, Tyr576, Tyr577, Tyr861) (Focal Adhesion
Associated Protein Tyrosine Kinase, BC3)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B |
|
| Focal Adhesion Kinase (FAK) is a non-receptor protein tyrosine kinase discovered as a substrate for Src and as a key element of integrin signaling. FAK plays a central role in cell spreading, differentiation, migration, cell death and acceleration of the G1 to S phase transition of the cell cycle. | | | Catalog # | F0019-55J | | Phosphorylation site-specific antibodies selective for the phosphorylated forms of focal adhesionkinase (FAK) enzyme containing a phosphate on tyrosine 397, 407, 576, 577 or 861. The antibodies have been shown to recognize FAK (approximately 125kD) in chick embryo fibroblast cells plated on fibronectin. | | Kit Components | F0019-55J1: FAK (pY397) 1x20ul | | F0019-55J2: FAK (pY407) 1x20ul | | F0019-55J3: FAK (pY576) 1x20ul | | F0019-55J4: FAK (pY577) 1x20ul | | F0019-55J5: FAK (pY861) 1x20ul | | Applications | Suitable for use in Western Blot and Immunostaining. Other applications not tested. | | Recommended Dilutions | Western Blot: 1:1000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | Not determined | | Form | Supplied as a liquid in Dulbecco’s PBS (without Mg2+ and Ca2+), 1mg/ml BSA (IgG, protease free), pH 7.3, 0.05% sodium azide, 50% glycerol. | | Purity | Purified by affinity chromatography | | Immunogen | Chemically synthesized phosphopeptides derived from the regions of FAK containing tyrosine at position 397, 407, 576, 577, or 861. | | Specificity | Recognizes phosphorylated forms of focal adhesion kinase (FAK) enzyme containing a phosphate on tyrosine 397, 407, 576, 577, or 861. The antibodies have been shown to recognize FAK (approximately 125kD) in chick embryo fibroblast cells plated on fibronectin. Species Crossreactivity: human, mouse, chicken and frog FAK. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
