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You are here:Home » Antibodies » Abs to Fanconi Proteins » Anti -Fanconi anemia C (FANCC, FLJ14675, FAC, FACC)

Anti -Fanconi anemia C (FANCC, FLJ14675, FAC, FACC)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit B
FANCC is a DNA repair protein that may operate in postreplication repair or a cell cycle checkpoint function. It may be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Hsp70 requires the cooperation of FANCC to suppress PKR activity and support survival of haematopoietic cells and FANCC does not require the multimeric Fanconi anemia complex to exert this function.
Catalog #F0019-58V7
Cellular Localization The major form is nuclear. The minor form is cytoplasmic.
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
ConcentrationNot determined
FormAs reported
PurityWhole antisera
ImmunogenA C-Terminal peptide within residues 450-558 of 558. Homology: 100% homology with human protein.
92% homology with rat and mouse proteins.
81% homology with bovine protein.
SpecificitySpecies Crossreactivity: This antibody reacts with the human protein.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesFanconi anemia group C protein, FAC, FACC


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