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You are here:Home » Antibodies » Abs to Fanconi Proteins » Anti -Fanconi anemia D2 (FA4, FACD, FAD, FAD2, FANCD2, Fanconi anemia Complementation Group D, Fanconi Pancytopenia Type 4)

Anti -Fanconi anemia D2 (FA4, FACD, FAD, FAD2, FANCD2, Fanconi anemia Complementation
Group D, Fanconi Pancytopenia Type 4)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
Fanconi anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects, progressive bone marrow failure, and cellular hypersensitivity to mitomycin C (MMC). The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation. DNA damage activates the monoubiquitination of FANCD2, targeting nuclear foci containing the BRCA1 protein.
Catalog #F0019-58W1
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG
Clone No8k150
HostMouse
SourceHuman
Concentration~1mg/ml
FormAs reported
PurityPurified by Protein G affinity chromatography.
ImmunogenHuman FANCD2 fusion protein.
SpecificityThis antibody is specific for FANCD2. Species Crossreactivity: Reacts with human FANCD2. Other species have not been tested.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesFA4, FACD, FAD, FAD2, FANCD, Fanconi anemia Complementation Group D, Fanconi Pancytopenia Type 4


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