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You are here:Home » Antibodies » Abs to DNA Replication, Repair » Anti -FANCJ (FANCJ protein, BACH 1, BACH1 BRIP1, BRIP 1, BRAC 1 Associated C Terminal Helicase 1, BRCA 1 Interacting Protein 1)

Anti -FANCJ (FANCJ protein, BACH 1, BACH1 BRIP1, BRIP 1, BRAC 1 Associated C Terminal
Helicase 1, BRCA 1 Interacting Protein 1)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse B
BRIP1 (also called BACH1) is a helicase that interacts with the BRCT domain of BRCA1 and has a role in BRCA1-dependent DNA repair and checkpoint. BRIP1 has recently been found to be defective in Fanconi anemia complementation group J. BRIP1/FANCJ has a function in the Fanconi anemia pathway that is independent of BRCA1 and downstream of FANCD2 activation. (1-4)
Catalog #F0019-58W9B
Positive Control HeLa whole and nuclear extracts, Raji whole cell extracts.
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No8k153
HostMouse
SourceHuman
Concentration~15mg/ml
FormAs reported
PurityAscites
ImmunogenFusion protein 647-1043 of human Brip1.
SpecificitySpecific for human Brip1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesFANCJ protein, BACH 1, BACH1 BRIP1, BRIP 1, BRAC 1 Associated C Terminal Helicase 1, BRCA 1 Interacting Protein 1


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