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You are here:Home » Antibodies » Abs to DNA Replication, Repair » Anti -FANCJ (FANCJ protein, BACH 1, BACH1, BRIP1, BRIP 1, BRAC 1 Associated C Terminal Helicase 1, BRCA 1 Interacting Protein 1)

Anti -FANCJ (FANCJ protein, BACH 1, BACH1, BRIP1, BRIP 1, BRAC 1 Associated C Terminal
Helicase 1, BRCA 1 Interacting Protein 1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit B IP
BRIP1 (also called BACH1 /FANCJ) is a helicase that interacts with the BRCT domain of BRCA1 and has a role in BRCA1-dependent DNA repair and checkpoint. BRIP1 has recently been found to be defective in Fanconi anemia complementation group J. BRIP1/FANCJ has a function in the Fanconi anemia pathway that is independent of BRCA1 and downstream of FANCD2 activation. (1-4)
Catalog #F0019-58W9C
Positive Control HeLa whole cell extract and Raji, 293, MCF7 and SKOV3 whole cell extracts.
ApplicationsSuitable for use in Western Blot and Immunoprecipitation. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
ConcentrationNot determined
FormAs reported
PurityWhole antisera
ImmunogenA synthetic peptide within the extreme C-terminus of the human FANCJ/BACH1/Brip1 protein sequence.
SpecificityThis antibody is specific for BACH1/Brip1/FANCJ. Species Crossreactivity: recognizes human Brip1/FANCJ
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesFANCJ protein, BACH 1, BACH1, BRIP1, BRIP 1, BRAC 1 Associated C Terminal Helicase 1, BRCA 1 Interacting Protein 1


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