| Fatty acids are important for general cellular metabolism. A number of proteins have been implicated in the transport and storage of fatty acid. FABPs (fatty acid binding proteins) are a group of cytoplasmic, small mol wt (14-15kD) and proteins that has widespread tissue distribution. FABPs can bind long-chain fatty acid, fatty-acid acyl-CoA and acyl-L-carnitine. Several different isoforms of FABP have been identified and generally referred to by tissue type (liver, heart, intestine, adipocyte, kidney, brain etc; protein designated as H-FABP indicates that it is heart type). However, expression of these isoforms is not exclusive and more than one isoforms can be found in a given cell or tissue. FABPs share significant degree of sequence homology. FABPs are also known as mammary derived growth inhibitor (MDGI), adipocyte lipid binding protein (ALBP), Myelin protein P2 homolog, P2 adipocyte protein, 422 protein (P15). |
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| Catalog # | F0019-73H |
| Applications | Suitable for use in Western Blot and ELISA. Other applications not tested. |
| Recommended Dilution | Western Blot: 1:1000-1:5000 |
| ELISA: 1:10,000-1:50,000. |
| Optimal dilutions to be determined by the researcher. |
| Recommended Control Peptide | F0019-77M: Fatty Acid Binding Protein, Human, Heart, Adipocyte, Human (FABP) Western Blot Control. |
| Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
| CAS Number | n/a |
| Clone Type | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Source | Rat |
| Concentration | Not determined |
| Form | Supplied as a liquid in PBS, 0.05% sodium azide, 40% glycerol. |
| Purity | Serum |
| Immunogen | A 20 aa synthetic peptide from rat adipocyte FABP (AFABP). Epitope: C-terminus. |
| Specificity | Recognizes rat adipocyte FABP. Species sequence homology |
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| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
