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Fatty Acid Binding Protein 5, Epidermal, Recombinant, Human (EFABP, FABP5, mal1, MGC133132)
Fatty Acid Binding Protein 5, Epidermal, Recombinant, Human (EFABP, FABP5, mal1, MGC133132)
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| FABP5 is a member of the intracellular fatty acid binding protein (FABP) family, which is known for the ability to specifically bind fatty acids (FAs) with high affinity for stearic and linoleic acids. FABP5 is expressed in endothelial cells of the microvasculature of the placenta, heart, skeletal muscle, small intestine, lung, and renal medulla. FABP4 and FABP5 are closely related and both are expressed in adipocytes. Absence of FABP5 resulted in increased systemic insulin sensitivity in two models of obesity and insulin resistance. | | | Catalog # | F0019-73J | | Recombinant human FABP5, aa1-135, was expressed in E. coli and purified by conventional chromatography. | | AA Sequence | MATVQQLEGR WRLVDSKGFD EYMKELGVGI ALRKMGAMAK PDCIITCDGK NLTIKTESTL KTTQFSCTLG EKFEETTADG RKTQTVCNFT DGALVQHQEW | | DGKESTITRK LKDGKLVVEC VMNNVTCTRI YEKVE | | Applications | Suitable for use in Western Blot and ELISA. Other applications have not been tested. | | Optimal dilutions to be deter | | Recommended Dilutions | Optimal dilutions to be determined by researchermined by researcher | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | 15.2kD | | Source | Human recombinant protein expressed in E. coli. | | Purity | ~90% (SDS-PAGE) | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in 20mM Tris pH 8.0, 1mM DTT, 20% glycerol. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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