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You are here:Home » Antibodies » Abs to Fatty Acid Binding Protein » Anti -Fatty Acid Binding Protein, Heart (BSA, Azide Free) (FABP)

Anti -Fatty Acid Binding Protein, Heart (BSA, Azide Free) (FABP)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IP
The human Fatty Acid Binding Protein is derived from the human FABP3 gene. FABPs are small intracellular proteins (~13-14kD) with a high degree of tissue specificity that bind long chain fatty acids. They are abundantly present in various cell types and play an important role in the intracellular utilization of fatty acids, transport and metabolism. There are at least nine distinct types of FABP, each showing a specific pattern of tissue expression. Due to its small size, FABP leaks rapidly out of ischemically damaged necrotic cells leading to a rise in serum levels. Ischemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. H-FABP is localized in the heart, skeletal and smooth muscle, mammary epithelial cells, aorta, distal tubules of the kidney, lung, brain, placenta, and ovary. It is also useful as marker for brain damage.
Catalog #F0019-75H1
ApplicationsSuitable for use in ELISA, Immunoprecipitation, Western Blot and Purification. Other applications not tested.
Recommended DilutionWestern Blot: 1:50 using reduced conditions. Detected a band of ~15kD.
Optimal dilutions to be determined by the researcher.
Positive ControlHeart cells, recombinant human FABP
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No6A546
HostMouse
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS. Available with BSA and sodium azide. See F0019-75H.
PurityPurified by Protein G affinity chromatography.
ImmunogenPurified human Fatty Acid Binding Protein, Heart (FABP).
SpecificityRecognizes human heart FABP of both natural and recombinant origin. Does not bind to human intestinal or liver FABP. Can be used to detect ischemia areas of human heart. Species Crossreactivity: rat, mouse and porcine
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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