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You are here:Home » Antibodies » Abs to Fatty Acid Binding Protein » Anti -Fatty Acid Binding Protein, Heart (FABP) (Biotin)

Anti -Fatty Acid Binding Protein, Heart (FABP) (Biotin)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IP IH
FABP is a plasma marker of acute myocardial infarction (AMI). The plasma kinetics of FABP (15kD) closely resemble those of myoglobin in that elevated plasma concentrations are found within 2 hours after AMI and return to normal generally within 18 to 24 hours. The concentration of FABP in the skeletal muscle is 20 times lower than in cardiac tissue (for myoglobin the same content for cardiac and skeletal tissue), making FABP cardiac-specific cf. myoglobin. This makes FABP a useful biochemical marker for the early assessment or exclusion of AMI. FABP also appears a useful plasma marker for the estimation of myocardial infarct size.
Catalog #F0019-75L
ApplicationsAnti-human heart FABP is useful for immunoassays, Immunoprecipitation, Immunohistology of frozen sections, Western Blots and for purification.
Recommended DilutionImmunohistology: 1:10
Western Blot: 1:10
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20°C or colder. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No6A548
HostMouse
SourceHuman
Concentration~0.1mg/ml
ImmunogenPurified human H-FABP
FormSupplied as a liquid in PBS, containing 0.02% sodium azide and 0.1% BSA. Conjugated to Biotin.
PurityPurified IgG
SpecificityRecognizes human heart FABP. Shows no binding to human intestinal or liver FABP. Stains heart muscle cells and striated skeletal muscle cells in immunohistology. Can be used to detect ischemia areas of human heart. Crossreactive with rat and mouse H-FABP.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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