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Anti -Fatty Acid Binding Protein, Liver (FABP)
Anti -Fatty Acid Binding Protein, Liver (FABP)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IP IH IF |
|
| The L-FABP protein is derived from the human FABP1 gene. FABPs are small intracellular proteins (~13-14kD) with a high degree of tissue specificity that bind long chain fatty | | | acids. They are abundantly present in various cell types and play an important role in the intracellular utilization of fatty acids, transport and metabolism. There are at least nine distinct types of FABP, each showing a specific pattern of tissue expression. Due to its small size, FABP leaks rapidly out of | | | ischemically damaged necrotic cells leading to a rise in serum levels. Ischemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. L-FABP is localized in hepatocytes and brush cells found in the biliary tract, in mucosa of small | | | and large intestine and in intestinal metaplasia of the gastric mucosa. Furthermore, L-FABP is present in the epithelium of the proximal tubule of the kidney. | | | Catalog # | F0019-76P1 | | Applications | Suitable for use in Western Blot, Immunoprecipitation, Immunofluorescence and Immunohistochemistry. Other applications have not been tested. | | Recommended Dilutions | Western Blot: 1:50 | | Immunohistochemistry (Frozen, paraffin): 1:50 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.1mg/ml | | Form | Supplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Specificity | Recognizes both native and recombinant human liver fatty acid binding protein (L-FABP). | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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