Anti -Fatty Acid Binding Protein, Heart, Adipocyte (FABP)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Serum |
E B |
|
| Fatty acids are important for general cellular metabolism. A number of proteins have been implicated in the transport and storage of fatty acid. FABPs (fatty acid binding proteins) are a group of cytoplasmic, small mol wt (14-15kD). FABP’s have a widespread tissue distribution. FABPs are quite abundant (3-5% of total cellular protein). At least 7 FABPs, FABP1-7, have been cloned and characterized from various tissues. FABPs can bind long-chain fatty acid, fatty-acid acyl-CoA and acyl-L-carnitine. Several different isoforms of FABP have been identified. These isoforms are generally referred to by tissue type (liver, heart, intestine, adipocyte, kidney, brain, etc. For example, protein designated as H-FABP indicates that it is heart type). Expression of these isoforms is not exclusive. More than one isoform can be found in a given cell or tissue. Three main types of FABPs that were initially discovered in the heart (FABP-H), liver (FABP-L), and intestine (FABP-I) are not exclusive to these tissues and show considerable differences at the amino acid level (~30% identity). Other FABPs detected in adipocyte, kidney, and brain show a high degree of sequence homology among each other and with other FABPs. | | | Catalog # | F0019-77 | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 1:1000-1:5000. | | ELISA: 1:1,000-1:10,000. Coat with 5-10ug F0019-77E. | | Optimal dilutions to be determined by the researcher. | | Control Peptides | F0019-77E: Fatty Acid Binding Protein, Heart, Adipocyte, Human (FABP), Control Peptide | | F0019-77M: Fatty Acid Binding Protein, Human, Heart, Adipocyte, Human (FABP) Western Blot Control | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | Not determined | | Form | Supplied as a liquid in 0.1% sodium azide, 40% glycerol. | | Purity | Serum | | Immunogen | 12aa synthetic peptide corresponding to the C-terminus of human FABP (KLH). | | Specificity | Recognizes Fatty Acid Binding Protein (FABP), Heart, Adipocyte. Isoform Sequence Homology | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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