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Fatty Acid Binding Protein 5, Epidermal, Recombinant, Human (EFABP, FABP5, mal1, MGC133132)
Fatty Acid Binding Protein 5, Epidermal, Recombinant, Human (EFABP, FABP5, mal1,
MGC133132)
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| Human Fatty Epidermal Acid Binding Protein FABP also called FABP-5 is a 15kD member of the intracellular fatty acid binding protein (FABP) family, which is known for the ability to bind fatty acids and related compounds ( bile acids or retinoids). in an internal cavity. The fatty acid binding proteins aP2 (fatty acid binding protein [FABP]-4) and mal1 (EFABP) are closely related and both are expressed in adipocytes. Absence of EFABP/mal1 resulted in increased systemic insulin sensitivity in two models of obesity and insulin resistance. Adipocytes isolated from mal1-deficient mice also exhibited enhanced insulin-stimulated glucose transport capacity. In contrast, mice expressing high levels of mal1 in adipose tissue display reduced systematic insulin activity. | | | Catalog # | F0019-86 | | Recombinant Human Epidermal Fatty Acid Binding Protein(FABP-5) is a monodimeric, non-glycosylated, polypeptide chain containing 135 amino acids and having a total molecular mass of 15200 Daltons. | | Specificity | The amino acid sequence of the recombinant human FABP5 is 100% homologous to the amino acid sequence of the human FABP-5. | | Applications | Western blotting, ELISA | | Reconstitution | Add 0.2 ml of dH20 and let the lyophilized pellet dissolve completely. | | Storage | Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid freeze-thaw cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. | | Molecular Weight | 15.2kD | | Source | E. coli | | Purity | 90% (SDS-PAGE); Two-step procedure using size exclusion chromatography before and after refolding. | | Concentration | ~0.5mg/ml | | Form | Supplied as a lyophilized powder in PBS. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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