Fatty Acid Binding Protein 2, aa1-132, Recombinant, Human (FABP2, Intestinal Fatty Acid
Binding Protein, mal1, MGC133132, FABPI, I-FABP 2)
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| FABP2, also known as intestinal fatty acid binding protein 2 (I-FABP), is expressed in the epithelium of the small intestine by mature enterocytes. FABP2 is thought to facilitate of cellular uptake and transport of long-chain fatty acids within enterocytes and may also help maintain energy homeostasis by functioning as a lipid sensor. This protein binds saturated long-chain fatty acid with a high affinity, but binds with a low affinity to unsaturated long-chain fatty acid. The Ala to Thr substitution at residue 54 of FABP2 is associated with higher total cholesterol, with stroke incidence, elevation of fasting and postprandial triglyceride, insulin resistance, and higher nonesterified fatty acid (NEFA) concentrations. | | | Catalog # | F0019-86B | | Source | Recombinant human FABP2, fused to His-tag at N-terminus, expressed in E.coli. | | Molecular Weight | 17.3kD (152aa) | | Endotoxin Level | 1.0 EU /1ug of protein (LAL). | | AA Sequence | MGSSHHHHHH SSGLVPRGSH MAFDSTWKVD RSENYDKFME KMGVNIVKRK LAAHDNLKLT ITQEGNKFTV KESSAFRNIE VVFELGVTFN YNLADGTELR GTWSLEGNKL IGKFKRTDNG NELNTVREII GDELVQTYVY EGVEAKRIFK KD | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | 17.3kD | | Source | E. coli | | Purity | 95% by SDS-PAGE | | Concentration | ~1.0mg/ml | | Form | Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0, 10% glycerol. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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