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You are here:Home » Antibodies » Abs to Fatty Acid Binding Protein » Anti -Fatty Acid Binding Protein 8 (FABP8, M [myelin]­FABP, P2, PMP2)

Anti -Fatty Acid Binding Protein 8 (FABP8, M [myelin]­FABP, P2, PMP2)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IH
FABP8 is a 15kD (predicted) member of the fatty acid binding protein family, calycin superfamily of molecules. It is found in Schwann cells, presumably on the cytoplasmic face of the plasma membrane where it may contribute to fatty acid transport across myelin. Functionally, FABP8 has a high affinity for U-shaped fatty acids such as oleic and palmitic acid. Human FABP8 is 132aa in length and exhibits two layers of antiparallel b-strands that envelope a hydrophobic pocket for lipid binding. Arg107 plus Arg127-Ile128-Tyr129 participate in fatty acid binding. Full length human FABP8 shares 87-95aa identity with mouse and rabbit FABP9, respectively.
Catalog #F0019-91
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 2ug/ml
Immunohistochemistry: 8-25ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No11n70
HostMouse
SourceHuman
ConcentrationNot determined
FormSupplied as a lyophilized powder in PBS, Trehalose. Reconstitute with sterile PBS to 0.5mg/ml.
PurityPurified by Protein A/G affinity chromatography.
ImmunogenRecombinant corresponding to aa2-132 from human FABP8/M-FABP expressed in E. coli (P02689).
SpecificityRecognizes human FABP8. No cross-reactivity with recombinant human FABP1, 2, 3, 4, 5, 6, 7, 9.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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