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You are here:Home » Antibodies » Abs to Ubiquitin Ligases » Anti -FBG3 (F-box 3)

Anti -FBG3 (F-box 3)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit B
F-box proteins, a critical component of the evolutionary conserved ubiquitin-protein ligase complex SCF (Skp1/Cdc53-Cullin1/F-box), recruit substrates for ubiquitination and consequent degradation through their specific protein-protein interaction domains. Novel human F-box proteins named FBG1, FBG2, FBG3, FBG4 and FBG5 constitute a third subfamily of mammalian F-box proteins. FBG genes are expressed in a limited number of human tissues including kidney, liver, brain and muscle tissues.
Catalog #F0019-98D2
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~1mg/ml
FormAs reported
PurityAs reported
ImmunogenA synthetic peptide containing residues 103-119 EWKVEDLSRDQRKEFPN) of the human FBG3 protein.
SpecificityFBG3 protein. Species Crossreactivity: Human. Cross-reactivity with rat and mouse is likely due to high homology (94%) between the immunogen and these rodent sequences.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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