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You are here:Home » Antibodies » Abs to Enzymes, Synthase » Anti -FASN (Fatty Acid Synthase)

Anti -FASN (Fatty Acid Synthase)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum B IP IH
FAS (Fatty Acid Synthase) is a central enzyme in de novo lipogenesis (triglyceride production). It is a target for SREBP and is upregulated by LXR activation. Fatty liver is often the result of FAS activation. It is also one of the accepted markers for insulin resistance and SREBP, LXR activation.
Catalog #F0020-11B
ApplicationsSuitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000 A band should be seen at ~272kD on SDS-PAGE. May see 1 or 2 minor cross-reacting lower MW bands in liver tissue.
Immunoprecipitation: 1:100
Immunohistochemistry: Paraffin
Optimal dilutions to be determined by the researcher.
Positive ControlMouse liver lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
Clone TypePolyclonal
HostRabbit
SourceMouse
ConcentrationAs reported
FormAs reported
PurityWhole antisera
ImmunogenAn internal synthetic peptide, conjugated to KLH, made near the N-terminus of the mouse FAS protein sequence.
SpecificitySpecific for FAS protein. Species Crossreactivity: human, porcine, chicken and mouse FAS. Other species have not been tested.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate names[Acyl-carrier-protein] S-acetyltransferase, [Acyl-carrier-protein] S-malonyltransferase, 3-hydroxypalmitoyl-[acyl-carrier-protein] Dehydratase, 3-oxoacyl-[acyl-carrier-protein] Reductase, 3-oxoacyl-[acyl-carrier-protein] Synthase, Enoyl-[acyl-carrier-prot


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