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You are here:Home » Antibodies » Abs to Ubiquitin Ligases » Anti -FBXL3 (F-box/LRR-repeat Protein 3, F-box and Leucine-rich Repeat Protein 3A, F-box/LRR-repeat Protein 3A, FBL3A, FBXL3A)

Anti -FBXL3 (F-box/LRR-repeat Protein 3, F-box and Leucine-rich Repeat Protein 3A,
F-box/LRR-repeat Protein 3A, FBL3A, FBXL3A)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
This gene encodes a member of the F-box protein family which is characterized by an approximately 40aa motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats and is localized in the nucleus.
Catalog #F0022-95C
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:32,000
Western Blot: 1-3ug/ml, observed in Human Adipose lysates on ~50-55kD bands
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to KRGGRDSDRNSSEE-C, from human FBXL3, at N-terminal (NP_036290.1).
SpecificityRecognizes human FBXL3. Species sequence homology: Canine, mouse, porcine and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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