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Abs to Ubiquitin Ligases
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Anti -FbxL10 (F-box and Leucine-rich Repeat Protein 10, F-box Protein, FBL10, PCCX2, Protein Containing CXXC Domain 2)
Anti -FbxL10 (F-box and Leucine-rich Repeat Protein 10, F-box Protein, FBL10, PCCX2,
Protein Containing CXXC Domain 2)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E B |
|
| PCCX1 encodes a nuclear protein carrying a PHD finger, a CXXC domain, and an acidic region. The CXXC domain was found to be sufficient for binding to DNA. The acidic region exhibits a high transactivation ability, but the full-length protein was inactive due to regions which inhibited the acidic region, including the C-terminal region. PCCX1 isactivated by proteolytic cleavage, which removes the C-terminal inhibitory region. | | | Catalog # | F0024-01 | | Application(s) | Suitable for use in peptide ELISA. In Western Blot no signal obtained yet but low background observed in Human Kidney and Brain extracts at up to 1ug/ml. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in TBS, pH 7.3, 0.5% BSA 0.02% sodium azide. | | Purity | Purified from goat serum by ammonium sulfate precipitation followed by immunoaffinity chromatography. | | Immunogen | Synthetic peptide: FGQVEEKLLQKLS, corresponding to amino acids 641-653 of Human FBX L10. | | Specificity | Recognizes human FbxL10. Expected to crossreact with Dictyostelium discoideum (82% identity with immunogen), Mouse (100% identity with immunogen) due to sequence homology. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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