Anti -FBXW7 (F-box and WD Repeat Domain Containing 7, F-box/WD Repeat-containing Protein
7, FBW7, Archipelago Homolog, AGO, hAgo, CDC4, hCdc4, F-box and WD-40 Domain-containing
Protein 7, F-box Protein FBX30, FBX30, FBXO30, FBXW6, FBW6, SEL10, SEL-10)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E B IH |
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| Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Involved in the degradation of cyclin-E, MYC, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1. | | | Catalog # | F0024-77D1 | | Applications | Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2a,k | | Clone No | 3D1 | | Host | Mouse | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2. | | Purity | Purified by Protein A affinity chromatography. | | Immunogen | Recombinant corresponding to aa599-708 from human FBXW7 with GST tag. MW of the GST tag alone is 26kD. | | Specificity | Recognizes human FBXW7. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -FBXW7 (F-box and WD Repeat Domain Containing 7, F-box/WD Repeat-containing Protein 7, FBW7, Archipelago Homolog, AGO, hAgo, CDC4, hCdc4, F-box and WD-40 Domain-containing Protein 7, F-box Protein FBX30, FBX30, FBXO30, FBXW6, FBW6, SEL10, SEL-10) |
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