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You are here:Home » Antibodies » Abs to Enzymes, Endonuclease » Anti -FEN1 (Flap Endonuclease 1, FEN-1, DNase IV, Flap Structure-specific Endonuclease 1, Maturation Factor 1, MF1, hFEN-1, RAD2)

Anti -FEN1 (Flap Endonuclease 1, FEN-1, DNase IV, Flap Structure-specific Endonuclease 1,
Maturation Factor 1, MF1, hFEN-1, RAD2)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IH
FEN-1 is a 42kD protein that functions as an endonuclease that cleaves branched DNA structures containing single-stranded 5' flaps or as an exonuclease on DNA nicks and gaps. FEN-1 endonuclease and exonuclease activities are stimulated by an association with proliferating cell nuclear antigen (PCNA) in the nucleus. FEN-1 is believed to have important roles in DNA replication and repair and is required in cell-free DNA replication systems.
Catalog #F0046-01
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No4E7
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS.
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant corresponding to aa1-380 from human FEN1 expressed in E. coli.
SpecificityRecognizes human FEN1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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