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Abs to Enzymes, Endonuclease
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Anti -FEN1 (Flap Endonuclease 1, FEN-1, DNase IV, Flap Structure-specific Endonuclease 1, Maturation Factor 1, MF1, hFEN-1, RAD2)
Anti -FEN1 (Flap Endonuclease 1, FEN-1, DNase IV, Flap Structure-specific Endonuclease 1,
Maturation Factor 1, MF1, hFEN-1, RAD2)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
B IH |
|
| FEN-1 is a 42kD protein that functions as an endonuclease that cleaves branched DNA structures containing single-stranded 5' flaps or as an exonuclease on DNA nicks and gaps. FEN-1 endonuclease and exonuclease activities are stimulated by an association with proliferating cell nuclear antigen (PCNA) in the nucleus. FEN-1 is believed to have important roles in DNA replication and repair and is required in cell-free DNA replication systems. | | | Catalog # | F0046-01 | | Applications | Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 4E7 | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Recombinant corresponding to aa1-380 from human FEN1 expressed in E. coli. | | Specificity | Recognizes human FEN1. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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