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Anti -FEZ2, IN (Fasciculation and elongation protein zeta 2, HUM3CL, MGC117372, Pre-T/NK cell-associated protein 3Cl, Zygin-2, Zygin II)
Anti -FEZ2, IN (Fasciculation and elongation protein zeta 2, HUM3CL, MGC117372, Pre-T/NK
cell-associated protein 3Cl, Zygin-2, Zygin II)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B |
|
| Fasciculation and elongation protein zeta-2 (FEZ2) is a homolog to the mammalian FEZ1, itself an ortholog of the C. elegans UNC-76 (1,2). In contrast to FEZ1, FEZ2 mRNA is widely expressed in mouse tissues. FEZ2 interacts with protein kinase C (PKC)- substrate and induces neurite extension of PC12 cells when co-expressed with a constitutively active form of PKC- , suggesting FEZ2 may play an important role in the morphological changes of various cells by associating with PKC- in a tissue non-specific manner (1). FEZ2 can interact with FEZ1 through its c- terminal regions and especially its coiled-coil region (5). At least two isoforms of FEZ2 are known to exist. | | | | | | Applications: | | | Suitable for use in Western Blot. Other applications not tested. | | | Catalog # | F3965-07 | | Recommended Dilution | Western Blot: 0.5–1ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid in PBS, 0.02% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to 15aa from near the center of human FEZ2 (Genbank accession No. NP_001036013). | | Specificity | Recognizes human FEZ2. Species crossreactivity: Mouse and rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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