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You are here:Home » Antibodies » Abs to Tyrosine Kinases » Anti -Fes (homolog of feline sarcoma oncogene)

Anti -Fes (homolog of feline sarcoma oncogene)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified B
Fes (homolog of feline sarcoma oncogene), also called c-Fes or c-Fps, is a 93kD protein within subgroup IV of the non-receptor tyrosine kinase family. It is expressed in myeloid hematopoietic cells, vascular endothelium and neurons, and regulates cell adhesion and extravasation. The 822 aa human Fes contains F-BAR (aa7-239), SH2 (aa460-549) and kinase (aa561-822) domains. The F-BAR domain contains coiled-coil homo-oligomerization and microtubule binding sequences. Within the region used as immunogen, human Fes shares 85% and 87% aa identity with mouse and rat Fes, respectively.
Catalog #F3965-65C
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 2ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
ConcentrationNot determined
FormSupplied as a lyophilized powder in PBS with 5% trehalose. Reconstitute with sterile PBS.
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant corresponding to human Fes expressed in E. coli (P07332).
SpecificityRecognizes human Fes.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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