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You are here:Home » Molecular Biology » MB-Binding Proteins » FKBP1B, Recombinant, Human, aa1-108, His-Tag (Peptidyl-prolyl Cis-trans Isomerase FKBP1B, PPIase FKBP1B, 12.6kD FK506-binding Protein, 12.6kD FKBP, FKBP-12.6, FK506-binding Protein 1B, FKBP-1B, Immunophilin FKBP12.6, Rotamase, h-FKBP-12, FKBP12.6, FKBP1L,

FKBP1B, Recombinant, Human, aa1-108, His-Tag (Peptidyl-prolyl Cis-trans Isomerase FKBP1B,
PPIase FKBP1B, 12.6kD FK506-binding Protein, 12.6kD FKBP, FKBP-12.6, FK506-binding Protein
1B, FKBP-1B, Immunophilin FKBP12.6, Rotamase, h-FKBP-12, FKBP12.6, FKBP1L,

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Specifications

FKBP1B, is a member of the immunophilin protein family which plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 (tacrolimus) and rapamycin (sirolimus). It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle.
Catalog #F4150-12G
SourceRecombinant corresponding to aa1-108 from human FKBP1B, fused to His-tag at N-terminal expressed in E.coli.
AA SequenceMGSSHHHHHH SSGLVPRGSH RSMGVEIETI SPGDGRTFPK KGQTCVVHYT GMLQNGKKFD SSRDRNKPFK FRIGKQEVIK GFEEGAAQMS LGQRAKLTCT PDVAYGATGH PGVIPPNATL IFDVELLNLE
Molecular Weight~14.2kD (MALDI-TOF)
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~14.2kD
SourceE.coli
Purity~90% (SDS-PAGE)
Concentration~0.1mg/ml
FormSupplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 20% glycerol, 1mM DTT.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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