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Specifications

Clone Host Grade Applications Polyclonal Goat Affinity Purified E

Fibrillin-2 is a part of the Fibrillin family of glycoproteins, which are essential factors in the formation and maintenance of elastic fibers known as microfibrils within the extracellular matrix. Various researchers have suggested that Fibrillin-2 has a role in the mediation of microfibril assembly during early elastogenesis. Defects in Fibrillin-2 are causal to a rare disorder involving autosomal dominant connective tissue known as congenital contractual arachnodactyly (CCA), also known as Beals syndrome or distal arthrogryposis type 9 (DA9), and is similar to Marfan syndrome.
Catalog #	F4195-11E
Applications	Suitable for use in ELISA. Other applications not tested.
Recommended Dilution	ELISA: 1:2000
	Optimal dilutions to be determined by the researcher.
Storage and Stability	May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Number	n/a
Clone Type	Polyclonal
Isotype	IgG
Host	Goat
Source	Mouse
Concentration	~0.5mg/ml
Form	Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
Purity	Purified by immunoaffinity chromatography.
Immunogen	Synthetic peptide corresponding to C-KELRKLEEHNEDD, from the internal region (near the C Terminus) of the protein sequence according to NP_034311.2.
Specificity	Recognizes Fibrillin 2. Species sequence homology: mouse.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.