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You are here:Home » Antibodies » Abs to Coagulation Factors » Anti -Fibrin Degradation Product, D-Dimer

Anti -Fibrin Degradation Product, D-Dimer

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
D-dimers are the principle degradation products of cross-linked fibrin, released into the bloodstream following the digestion of fibrin clots (thrombus) by the enzyme plasmin, and thus measurement of the level of D-dimer in plasma, can be used as an indication of thrombotic disorders. Conditions in which levels of D-dimer are elevated include deep vein thrombosis (DVT), venous thromboembolism (VTE), cardiovascular disease and disseminated intravascular coagulation (DIC), a possible acute condition arising from surgical operations, septic shock and liver disease.
Catalog #F4197-15T
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
HybridomaSp2/0 myeloma cells with spleen cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No10B2317
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenHomogenised fibrin clot.
SpecificityRecognizes human D-dimer and high molecular weight fibrin degradation products, but does not crossreact with fibrinogen (D-monomer).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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