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You are here:Home » Antibodies » Abs to Coagulation Factors » Anti -Fibrin Degradation Product, D-Dimer

Anti -Fibrin Degradation Product, D-Dimer

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
Human D-dimer (DD), a specific degradation product of cross-linked fibrin, is released into the bloodstream during clot breakdown. It is used as an indicator of a blood clots, venous thromboses or pulmonary embolisms.
Catalog #F4197-17
ApplicationsSuitable for use in ELISA, Western Blot and Immunoelectrophoresis. Other applications have not been tested.
Recommended DilutionSandwich ELISA: Plasma samples should be diluted with 10mM Tris-HCl buffer, pH 7.5, 1M sodium chloride, 0.1% Tween 20. To avoid non-specific binding, the final sodium chloride concentration in plasma samples should be 0.5M.
Optimal dilutions to be determined by the researcher.
Matched PairSuitable for use as the as the detection or conjugate (label) antibody.
Matched to F4197-15, F4197-19 and F4197-23 as the capture or solid phase antibody.
HydridomaHybridization of Sp2/0 myeloma cells with spleen cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add glycerol (40-50%) and aliquot. Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No1.B.671
HostMouse
SourceHuman
Concentration~5mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenHomogenized fibrin clot
SpecificityRecognizes human D-dimer (DD). Crossreacts with fibrinogen. Low crossreactivity with D-monomer.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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